Novel and classic myoepithelial/stem cell markers in metaplastic carcinomas of the breast
JS Reis-Filho, F Milanezi, J Paredes… - Applied …, 2003 - journals.lww.com
Metaplastic carcinomas of the breast (MCBs) are unusual neoplasms characterized by an
admixture of glandular epithelial components, which frequently exhibit features of squamous
differentiation, and mesenchymal malignant components. Regardless of the presence of
myoepithelial features in MCB, no consensus concerning their putative histogenesis has yet
been achieved. Recently, novel putative myoepithelial markers have been developed,
including p63, maspin, and P-cadherin. We assessed the expression of these myoepithelial …
admixture of glandular epithelial components, which frequently exhibit features of squamous
differentiation, and mesenchymal malignant components. Regardless of the presence of
myoepithelial features in MCB, no consensus concerning their putative histogenesis has yet
been achieved. Recently, novel putative myoepithelial markers have been developed,
including p63, maspin, and P-cadherin. We assessed the expression of these myoepithelial …