Signal transduction via the MAP kinases: proceed at your own RSK.
J Blenis - Proceedings of the National Academy of …, 1993 - National Acad Sciences
Proceedings of the National Academy of Sciences, 1993•National Acad Sciences
An explosion of new information linking activation of cell surface signal initiators to changes
in gene expression has recently emerged. The focus of much of this information has
centered around the agonist-dependent activation of the mitogen-activated protein (MAP)
kinases. Although this intracellular signal transduction pathway is extremely complex,
conservation of many of its components has been observed in yeast, nematodes,
Drosophila, and mammals. Thus, these signaling proteins may participate in the regulation …
in gene expression has recently emerged. The focus of much of this information has
centered around the agonist-dependent activation of the mitogen-activated protein (MAP)
kinases. Although this intracellular signal transduction pathway is extremely complex,
conservation of many of its components has been observed in yeast, nematodes,
Drosophila, and mammals. Thus, these signaling proteins may participate in the regulation …
An explosion of new information linking activation of cell surface signal initiators to changes in gene expression has recently emerged. The focus of much of this information has centered around the agonist-dependent activation of the mitogen-activated protein (MAP) kinases. Although this intracellular signal transduction pathway is extremely complex, conservation of many of its components has been observed in yeast, nematodes, Drosophila, and mammals. Thus, these signaling proteins may participate in the regulation of a variety of cellular processes.
National Acad Sciences