Serum Haemopexin Concentration in Patients with Various Haemoglobinopathies: Effect of Splenectomy

A Fertakis, G Panitsas, B Angelopoulos - Acta Haematologica, 1973 - karger.com
A Fertakis, G Panitsas, B Angelopoulos
Acta Haematologica, 1973karger.com
Serum haemopexin levels were determined by the radial immunodiffusion method in 96
patients with β-thalassaemia major (27 after splenectomy), in 36 with sickle cell disease and
in 18 with sickle cell-thalassaemia disease (4 after splenectomy). Lowering of haemopexin
concentration was extremely marked in thalassaemia major and–to a lesser extent–in sickle
cell and sickle cell-thalassaemia disease. Comparatively higher values were noted after
splenectomy
Abstract
Serum haemopexin levels were determined by the radial immunodiffusion method in 96 patients with β-thalassaemia major (27 after splenectomy), in 36 with sickle cell disease and in 18 with sickle cell-thalassaemia disease (4 after splenectomy). Lowering of haemopexin concentration was extremely marked in thalassaemia major and – to a lesser extent – in sickle cell and sickle cell-thalassaemia disease. Comparatively higher values were noted after splenectomy
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