Sex hormones and systemic lupus erythematosus
RG Lahita - Rheumatic Disease Clinics of North America, 2000 - Elsevier
Systemic lupus erythematosus (SLE) is a disease like most of the connective tissue
diseases, where the prevalence is greatest in young women of childbearing age. 8 This is
one of the most obvious clinical observations in both the human form of the disease and that
of certain animal models. Because of this, gender and age are most likely linked to both
cause andpathogenesis. Despite these facts, an explanation of this sexual predilection is
elusive, although there are many theories. Factors like sex hormones60 and genetics85 are …
diseases, where the prevalence is greatest in young women of childbearing age. 8 This is
one of the most obvious clinical observations in both the human form of the disease and that
of certain animal models. Because of this, gender and age are most likely linked to both
cause andpathogenesis. Despite these facts, an explanation of this sexual predilection is
elusive, although there are many theories. Factors like sex hormones60 and genetics85 are …