Effects of cocaine on cortisol secretion in humans
CM Heesch, BH Negus, RW Snyder II… - The American journal of …, 1995 - Elsevier
The effects of acute cocaine administration on the pituitary adrenal axis in humans without a
history of drug abuse are unknown. The authors studied 12 male volunteers twice in a
double-blinded, placebo-controlled, randomized fashion. After intranasal administration of 2
mg/kg cocaine, cortisol levels were significantly higher than after placebo administration.
The authors concluded that acute administration of cocaine to humans increases cortisol
secretion.
history of drug abuse are unknown. The authors studied 12 male volunteers twice in a
double-blinded, placebo-controlled, randomized fashion. After intranasal administration of 2
mg/kg cocaine, cortisol levels were significantly higher than after placebo administration.
The authors concluded that acute administration of cocaine to humans increases cortisol
secretion.