Possible multicentric occurrence of hepatocellular carcinoma: a clinicopathological study

K Takenaka, E Adachi, T Nishizaki, K Hiroshige… - Hepatology, 1994 - journals.lww.com
To assess the features of multicentric occurrence in hepatocellular carcinoma, we analyzed
10 of 72 patients (14%) who had undergone hepatic resection for hepatocellular carcinoma
from May 1989 to October 1992 both clinically and pathologically. The multicentric
occurrence of hepatocellular carcinoma was defined among the simultaneously detected
small tumors as (a) at least one tumor consisting of extremely well-differentiated (grade I)
hepatocellular carcinoma growing in a replacing pattern or (b) one of a group of …