The insulin resistant state is a major risk factor for coronary artery disease. This increased
risk is likely to be due to associated lipid and coagulation abnormalities rather than just
abnormalities in glucose metabolism or hyperinsulinaemia alone. Exaggerated postprandial
lipaemia is a well-recognised associate of insulin resistance and postprandial
hypertriglyceridaemia is particularly important in the development of coronary atheroma. It
seems likely that insulin is one of the hormonal regulators of adipose tissue and skeletal …