The heritability of otitis media: a twin and triplet study

ML Casselbrant, EM Mandel, PA Fall, HE Rockette… - Jama, 1999 - jamanetwork.com
ContextAnatomical, physiological, and epidemiological data indicate that there may be a
significant genetic component to prolonged time with and recurrent episodes of otitis media
in children. ObjectiveTo determine the genetic component of time with and episodes of
middle ear effusion and acute otitis media (AOM) during the first 2 years of life.
DesignProspective twin and triplet cohort study with enrollment from 1982 through 1995.
SettingOtitis Media Research Center in the ear, nose, and throat clinic of Children's Hospital …