An inherited defect in the C3 convertase, C3b, Bb, associated with glomerulonephritis

HK Marder, TH Coleman, J Forristal, L Beischel… - Kidney international, 1983 - Elsevier
HK Marder, TH Coleman, J Forristal, L Beischel, CD West
Kidney international, 1983Elsevier
Methods Complement protein measurements. Studies were done on serum from blood
allowed to clot at room temperature or plasma (citrate phosphate dextrose adenine), both
stored at—70 C. Measurements of Clq, C2, C4, C3, factor B, H, I, and C4 binding protein
(C4bp) were by radial immunodiffusion (RID)[17, 181 using goat antiserum produced in this
laboratory. Ring diameters were measured with a lOx binocular micro-
Methods Complement protein measurements. Studies were done on serum from blood allowed to clot at room temperature or plasma (citrate phosphate dextrose adenine), both stored at—70 C. Measurements of Clq, C2, C4, C3, factor B, H, I, and C4 binding protein (C4bp) were by radial immunodiffusion (RID)[17, 181 using goat antiserum produced in this laboratory. Ring diameters were measured with a lOx binocular micro-
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