Publisher Summary This chapter discusses separate pools of CNS zinc, which are, vesicular
zinc, free zinc, and protein-bound zinc. Vesicular zinc is the one which is sequestered in the
presynaptic vesicles of a special class of neurons, the zinc-containing neurons, which are
found primarily in limbic, cerebrocortical, and corticofugal systems. This vesicular zinc can
be selectively stained by several histochemical procedures and is, therefore, accessible to
histological and histoanalytical studies. The second pool, free zinc, is an entirely …