Serum neurotrophin concentrations in autism and mental retardation: a pilot study
K Miyazaki, N Narita, R Sakuta, T Miyahara… - Brain and …, 2004 - Elsevier
To evaluate the availability of the serum neurotrophins for the diagnosis of the patients with
neurodevelopmental disorder, we measured the serum concentration of brain-derived
neurotrophic factor (BDNF) and neurotrophin-4 (NT-4) in the patients diagnosed with autism
(n= 18) and mental retardation (n= 20), or healthy controls (n= 16), using enzyme-linked
immunosorbent assay. There tended to be a higher concentration of serum BDNF found in
the autistic group (P< 0.05 by analysis of variance (ANOVA)) and the mental retardation …
neurodevelopmental disorder, we measured the serum concentration of brain-derived
neurotrophic factor (BDNF) and neurotrophin-4 (NT-4) in the patients diagnosed with autism
(n= 18) and mental retardation (n= 20), or healthy controls (n= 16), using enzyme-linked
immunosorbent assay. There tended to be a higher concentration of serum BDNF found in
the autistic group (P< 0.05 by analysis of variance (ANOVA)) and the mental retardation …