Detection of aldehydes in bronchoalveolar lavage of rats exposed to ozone
WA Pryor, E Bermúdez, R Cueto… - Fundamental and Applied …, 1996 - Elsevier
We report the detection of hexanal, heptanal, and nonanal in the bronchoalveolar lavage
(BAL) of rats exposed to 0.5 to 10 ppm ozone with or without simultaneous 5% CO2. These
three aldehydes primarily result from the Criegee ozonation of specific mono-or
polyunsaturated fatty acids that are present in significant amounts in the rat lung; eg,
palmitoleic acid gives heptanal, oleic gives nonanal, and linoleic and arachidonic can give
hexanal. Hexanal also is produced in the ozone-initiated autoxidation of any n-6 …
(BAL) of rats exposed to 0.5 to 10 ppm ozone with or without simultaneous 5% CO2. These
three aldehydes primarily result from the Criegee ozonation of specific mono-or
polyunsaturated fatty acids that are present in significant amounts in the rat lung; eg,
palmitoleic acid gives heptanal, oleic gives nonanal, and linoleic and arachidonic can give
hexanal. Hexanal also is produced in the ozone-initiated autoxidation of any n-6 …