Recruitment of marrow-derived endothelial cells to experimental choroidal neovascularization by local expression of vascular endothelial growth factor
KG Csaky, JZ Baffi, GA Byrnes, JD Wolfe… - Experimental eye …, 2004 - Elsevier
Purpose. The question of whether adult animals maintain a reservoir of endothelial
progenitor cells (EPCs) in the bone marrow that is involved in neovascularization is under
investigation. The following study was undertaken to examine the potential contribution of
EPCs to the development of choroidal neovascularization (CNV) in adult mice and to
examine the role of local expression of vascular endothelial growth factor (VEGF) in this
process. Methods. Lethally irradiated, adult female nude mice were engrafted with whole …
progenitor cells (EPCs) in the bone marrow that is involved in neovascularization is under
investigation. The following study was undertaken to examine the potential contribution of
EPCs to the development of choroidal neovascularization (CNV) in adult mice and to
examine the role of local expression of vascular endothelial growth factor (VEGF) in this
process. Methods. Lethally irradiated, adult female nude mice were engrafted with whole …