T” RESPONSE to tissue injury comprises a series of events which are relatively similar
irrespective of the tissue involved, although each organ contains specialized cells and
distinctive extracellular matrices which impart some specificity. Thus, recruitment of
inflammatory cells is the first event following injury, and is directed at neutralizing the
damaging agents and removing necrotic tissue. This is followed by proliferation and
migration of myofibroblast-like cells, which penetrate the wound and secrete extracellular …