[PDF][PDF] Increase in caudate nuclei volumes of first-episode schizophrenic patients taking antipsychotic drugs
MH Chakos, JA Lieberman, RM Bilder… - American Journal of …, 1994 - psychrights.org
Objective: This study examined the pathomorphology of the caudate nuclei in first-episode
schizophrenic patients with minimal previous neuroleptic exposure. Method: Magnetic
resonance imaging (MRI) of the brain was used to examine longitudinally the caudate
pathomorphology in 29 first-episode schizophrenic patients and 10 healthy comparison
subjects. MRI scans were obtained after the subjects entered the study and at 18-month
follow-up. The patients were treated with standardized neuroleptic regimens during the 18 …
schizophrenic patients with minimal previous neuroleptic exposure. Method: Magnetic
resonance imaging (MRI) of the brain was used to examine longitudinally the caudate
pathomorphology in 29 first-episode schizophrenic patients and 10 healthy comparison
subjects. MRI scans were obtained after the subjects entered the study and at 18-month
follow-up. The patients were treated with standardized neuroleptic regimens during the 18 …