Natural human antibodies to gram-negative bacteria: immunoglobulins G, A, and M
IR Cohen, LC Norins - Science, 1966 - science.org
IR Cohen, LC Norins
Science, 1966•science.orgSignificant amounts of immunoglobulins G and M, and a small amount of natural antibodies
reactive with Neisseria gonorrhoeae and Escherichia coli, have been detected in human
adult serums by immunofluorescent techniques. Umbilical cord serums also contained
substantial immunoglobulin-G antibody but little or no M or A. These findings challenge the
concept that natural antibodies reactive with Gram-negative bacteria are primarily of the
immunoglobulin-M class.
reactive with Neisseria gonorrhoeae and Escherichia coli, have been detected in human
adult serums by immunofluorescent techniques. Umbilical cord serums also contained
substantial immunoglobulin-G antibody but little or no M or A. These findings challenge the
concept that natural antibodies reactive with Gram-negative bacteria are primarily of the
immunoglobulin-M class.
Significant amounts of immunoglobulins G and M, and a small amount of natural antibodies reactive with Neisseria gonorrhoeae and Escherichia coli, have been detected in human adult serums by immunofluorescent techniques. Umbilical cord serums also contained substantial immunoglobulin-G antibody but little or no M or A. These findings challenge the concept that natural antibodies reactive with Gram-negative bacteria are primarily of the immunoglobulin-M class.
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