Relation between non-uniform hemodynamics and sites of altered permeability and lesion growth at the rabbit aorto-celiac junction
JR Buchanan Jr, C Kleinstreuer, GA Truskey, M Lei - Atherosclerosis, 1999 - Elsevier
Using the rabbit's aorto-celiac junction as a representative atherosclerotic model, the
hemodynamics of a bifurcating blood vessel are numerically simulated and three
hemodynamic parameters are compared. The wall shear stress (WSS), the oscillatory shear
index (OSI), and the spatial wall shear stress gradient (WSSG) are considered in this study.
Locally enhanced wall permeabilities and intimal macrophages are generally considered to
be involved in atherogenesis, and here the primary concern is with the hemodynamic …
hemodynamics of a bifurcating blood vessel are numerically simulated and three
hemodynamic parameters are compared. The wall shear stress (WSS), the oscillatory shear
index (OSI), and the spatial wall shear stress gradient (WSSG) are considered in this study.
Locally enhanced wall permeabilities and intimal macrophages are generally considered to
be involved in atherogenesis, and here the primary concern is with the hemodynamic …