Changes in gene expression during progression of ovarian carcinoma

J Tapper, E Kettunen, M Seppälä, LC Andersson… - Cancer genetics and …, 2001 - Elsevier
The molecular events leading to the development and progression of serous ovarian
carcinoma are not completely understood. We performed a large scale survey for the
identification of differentially expressed genes in serous ovarian carcinoma by using cDNA
array analysis. Differences in gene expression between serous adenocarcinoma and
benign serous adenoma, and between advanced and/or moderately or poorly differentiated
and local, highly differentiated serous adenocarcinoma were assessed. The most striking …