[HTML][HTML] Rabbit serum paraoxonase 3 (PON3) is a high density lipoprotein-associated lactonase and protects low density lipoprotein against oxidation
DI Draganov, PL Stetson, CE Watson… - Journal of Biological …, 2000 - ASBMB
The paraoxonase gene family contains at least three members: PON1, PON2, andPON3.
The physiological roles of the corresponding gene products are still uncertain. Until recently,
only the serum paraoxonase/arylesterase (PON1) had been purified and characterized.
Here we report the purification, cloning, and characterization of rabbit serum PON3. PON3 is
a 40-kDa protein associated with the high density lipoprotein fraction of serum. In contrast to
PON1, PON3 has very limited arylesterase and no paraoxonase activities but rapidly …
The physiological roles of the corresponding gene products are still uncertain. Until recently,
only the serum paraoxonase/arylesterase (PON1) had been purified and characterized.
Here we report the purification, cloning, and characterization of rabbit serum PON3. PON3 is
a 40-kDa protein associated with the high density lipoprotein fraction of serum. In contrast to
PON1, PON3 has very limited arylesterase and no paraoxonase activities but rapidly …