Background: The role of platelets in inflammation is recognized but poorly characterized,
and little is known of their interaction with leukocytes. However, platelet-leukocyte
interactions have been demonstrated in cardiovascular disease, culminating in enhanced
leukocyte recruitment. Objectives: This study was undertaken to assess the possibility and
potential role of similar phenomena occurring in asthmatic patients, a murine model of
allergic inflammation, and in vitro adhesion studies. Methods: Asthmatic patients had blood …