lnterleukin-8 and related chemotactic cytokines—CXC and CC chemokines
M Baggiolini, B Dewald, B Moser - Advances in immunology, 1993 - Elsevier
Publisher Summary This chapter focuses on interleukin-8 (IL-8) and related chemotactic
cytokines—namely, CXC and CC chemokines. IL-8 is the best known member of a new
class of cytokines that are widely studied because of their ability to attract and activate
leukocytes, and their potential role as mediators of inflammation. IL-8 was originally isolated
from the culture supernatants of stimulated human blood monocytes and was identified as a
protein of 72 amino acids with a molecular weight of 8383. The three-dimensional structure …
cytokines—namely, CXC and CC chemokines. IL-8 is the best known member of a new
class of cytokines that are widely studied because of their ability to attract and activate
leukocytes, and their potential role as mediators of inflammation. IL-8 was originally isolated
from the culture supernatants of stimulated human blood monocytes and was identified as a
protein of 72 amino acids with a molecular weight of 8383. The three-dimensional structure …