Are megakaryocytes and endothelial cells sisters?
ZC Han, JP Caen - The Journal of laboratory and clinical …, 1993 - translationalres.com
Megakaryocytes and endothelial cells, two important blood and vascular cells, share many
similar antigens on their surfaces and in the cytoplasm. It is known that the two types of cells
share several developmental regulators: fibroblast growth factors, granulocyte-macrophage
colony-stimulating factor, heparin and heparan sulfate, platelet factor 4, transforming growth
factor-β, γ-interferon, and thrombospondin. Recognition of these common factors and
studies with them are broadening the understanding of the pathogenesis of megakaryocytic …
similar antigens on their surfaces and in the cytoplasm. It is known that the two types of cells
share several developmental regulators: fibroblast growth factors, granulocyte-macrophage
colony-stimulating factor, heparin and heparan sulfate, platelet factor 4, transforming growth
factor-β, γ-interferon, and thrombospondin. Recognition of these common factors and
studies with them are broadening the understanding of the pathogenesis of megakaryocytic …