[CITATION][C] Brain activation by histamine prick test‐induced itch

B Walter, MN Sadlo, J Kupfer… - Journal of General …, 2005 - Wiley Online Library
B Walter, MN Sadlo, J Kupfer, V Niemeier, B Brosig, R Stark, D Vaitl, U Gieler
Journal of General Internal Medicine, 2005Wiley Online Library
Results Flare, wheal, and itch Following histamine prick, a substantial local reaction was
observed. The mean diameter of flares reached 24 mm and showed a maximum about 5 min
after prick. Mean wheal diameters increased continuously up to 6 mm at the end of the
session. After saline prick, the flare was considerably smaller and a wheal was never
detected. Accordingly, ratings of itch intensity and unpleasantness were much higher after
histamine than after the saline prick (see Fig 1).
Results
Flare, wheal, and itch Following histamine prick, a substantial local reaction was observed. The mean diameter of flares reached 24 mm and showed a maximum about 5 min after prick. Mean wheal diameters increased continuously up to 6 mm at the end of the session. After saline prick, the flare was considerably smaller and a wheal was never detected. Accordingly, ratings of itch intensity and unpleasantness were much higher after histamine than after the saline prick (see Fig 1).
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