[CITATION][C] Nerve growth factor (NGF) and epidermal nerve fibers in atopic dermatitis model NC/Nga mice
Y Horiuchi, SJ Bae, I Katayama - Journal of dermatological science, 2005 - jdsjournal.com
Atopic dermatitis (AD) may be exacerbated by psycho-and/or physiological stress, such as
itching which prompts scratching of the affected skin [1]. Various itch-inducement factors [2]
have been reported though the pathophysiological mechanisms are but poorly understood.
NC/Nga mice [3], as a model of AD, display fierce scratching [4] with consequent hair loss
from the head and back, followed by deep excoriation. These animals should thus prove
quite suitable as a model for examining the pathophysiological mechanisms of itching [2, 4] …
itching which prompts scratching of the affected skin [1]. Various itch-inducement factors [2]
have been reported though the pathophysiological mechanisms are but poorly understood.
NC/Nga mice [3], as a model of AD, display fierce scratching [4] with consequent hair loss
from the head and back, followed by deep excoriation. These animals should thus prove
quite suitable as a model for examining the pathophysiological mechanisms of itching [2, 4] …