Formation of cholesterol-and apoprotein E-enriched high density lipoproteins in vitro.
V Gordon, TL Innerarity, RW Mahley - Journal of Biological Chemistry, 1983 - ASBMB
The delivery of cholesterol to canine serum or plasma altered the distribution of cholesterol
and apoproteins in subclasses of high density lipoproteins (HDL). In these experiments, two
in vitro systems were employed. The first system used cholesterol-celite particles to deliver
cholesterol to canine plasma during 4-h incubations. When the cholesterol distribution in the
lipoproteins was analyzed by Geon-Pevikon electrophoresis, an increase in cholesterol
content was found in the slower migrating subclasses of HDL (HDL1 and HDLc). A large …
and apoproteins in subclasses of high density lipoproteins (HDL). In these experiments, two
in vitro systems were employed. The first system used cholesterol-celite particles to deliver
cholesterol to canine plasma during 4-h incubations. When the cholesterol distribution in the
lipoproteins was analyzed by Geon-Pevikon electrophoresis, an increase in cholesterol
content was found in the slower migrating subclasses of HDL (HDL1 and HDLc). A large …