Relapsing-remitting multiple sclerosis and human herpesvirus 6 active infection
R Álvarez-Lafuente, V De las Heras… - Archives of …, 2004 - jamanetwork.com
Background Recent studies have focused on the relationship between human herpesvirus 6
(HHV-6) and multiple sclerosis (MS). Objective To analyze HHV-6 messenger RNA
expression in patients with relapsing-remitting (RR) MS vs healthy blood donors (HBDs).
Design One hundred fifty-four subjects were enrolled in the study: 105 patients with RRMS
(32 in relapse) and 49 HBDs. Total DNA and messenger RNA were extracted from serum
and blood samples, respectively, and analyzed by quantitative real-time reverse …
(HHV-6) and multiple sclerosis (MS). Objective To analyze HHV-6 messenger RNA
expression in patients with relapsing-remitting (RR) MS vs healthy blood donors (HBDs).
Design One hundred fifty-four subjects were enrolled in the study: 105 patients with RRMS
(32 in relapse) and 49 HBDs. Total DNA and messenger RNA were extracted from serum
and blood samples, respectively, and analyzed by quantitative real-time reverse …