[HTML][HTML] Expression of caveolin-1 is required for the transport of caveolin-2 to the plasma membrane: retention of caveolin-2 at the level of the golgi complex
I Parolini, M Sargiacomo, F Galbiati, G Rizzo… - Journal of Biological …, 1999 - ASBMB
Caveolins-1 and-2 are normally co-expressed, and they form a hetero-oligomeric complex in
many cell types. These caveolin hetero-oligomers are thought to represent the assembly
units that drive caveolae formation in vivo. However, the functional significance of the
interaction between caveolins-1 and-2 remains unknown. Here, we show that caveolin-1 co-
expression is required for the transport of caveolin-2 from the Golgi complex to the plasma
membrane. We identified a human erythroleukemic cell line, K562, that expresses caveolin …
many cell types. These caveolin hetero-oligomers are thought to represent the assembly
units that drive caveolae formation in vivo. However, the functional significance of the
interaction between caveolins-1 and-2 remains unknown. Here, we show that caveolin-1 co-
expression is required for the transport of caveolin-2 from the Golgi complex to the plasma
membrane. We identified a human erythroleukemic cell line, K562, that expresses caveolin …