Role of fracture hematoma and periosteum during fracture healing in rats: interaction of fracture hematoma and the periosteum in the initial step of the healing process
A Ozaki, M Tsunoda, S Kinoshita, R Saura - Journal of orthopaedic science, 2000 - Elsevier
To study the mechanisms of fracture healing, we investigated the interaction between
fracture hematoma and periosteum during the early phase of fracture healing in rats.
Experimentally induced fractures of the tibia in untreated rats were compared histologically
with such fractures in rats in which either the bone marrow or the periosteum had been
removed. The extent of periosteal cell proliferation and chondrogenesis in the fracture
hematoma was evaluated on experimental days 3, 6, 10, and 14. On day 3, periosteal cell …
fracture hematoma and periosteum during the early phase of fracture healing in rats.
Experimentally induced fractures of the tibia in untreated rats were compared histologically
with such fractures in rats in which either the bone marrow or the periosteum had been
removed. The extent of periosteal cell proliferation and chondrogenesis in the fracture
hematoma was evaluated on experimental days 3, 6, 10, and 14. On day 3, periosteal cell …