Prognostic significance of left ventricular mass change during treatment of hypertension
RB Devereux, K Wachtell, E Gerdts, K Boman… - Jama, 2004 - jamanetwork.com
ContextIncreased baseline left ventricular (LV) mass predicts cardiovascular (CV)
complications of hypertension, but the relation between lower LV mass and outcome during
treatment for hypertension is uncertain. ObjectiveTo determine whether reduction of LV
mass during antihypertensive treatment modifies risk of major CV events independent of
blood pressure change. Design, Setting, and ParticipantsProspective cohort substudy of the
Losartan Intervention For Endpoint Reduction in Hypertension (LIFE) randomized clinical …
complications of hypertension, but the relation between lower LV mass and outcome during
treatment for hypertension is uncertain. ObjectiveTo determine whether reduction of LV
mass during antihypertensive treatment modifies risk of major CV events independent of
blood pressure change. Design, Setting, and ParticipantsProspective cohort substudy of the
Losartan Intervention For Endpoint Reduction in Hypertension (LIFE) randomized clinical …