[HTML][HTML] Phosphorylated α-synuclein is ubiquitinated in α-synucleinopathy lesions
M Hasegawa, H Fujiwara, T Nonaka… - Journal of Biological …, 2002 - ASBMB
α-Synuclein is one of the major components of intracellular fibrillary aggregates in the brains
of a subset of neurodegenerative disorders, including Parkinson's disease, dementia with
Lewy bodies, multiple system atrophy, and Hallervorden-Spatz disease, which are referred
to as α-synucleinopathies. We have shown previously (Fujiwara, H., Hasegawa, M.,
Dohmae, N., Kawashima, A., Masliah, E., Goldberg, MS, Shen, J., Takio, K., and Iwatsubo,
T.(2002) Nat. Cell Biol. 4, 160–164) that α-synuclein deposited in synucleinopathy brains is …
of a subset of neurodegenerative disorders, including Parkinson's disease, dementia with
Lewy bodies, multiple system atrophy, and Hallervorden-Spatz disease, which are referred
to as α-synucleinopathies. We have shown previously (Fujiwara, H., Hasegawa, M.,
Dohmae, N., Kawashima, A., Masliah, E., Goldberg, MS, Shen, J., Takio, K., and Iwatsubo,
T.(2002) Nat. Cell Biol. 4, 160–164) that α-synuclein deposited in synucleinopathy brains is …