Cohort analysis of Parkinson's syndrome: evidence for a single etiology related to subclinical infection about 1920

DC Poskanzer, RS Schwab - Journal of chronic diseases, 1963 - Elsevier
Cohort analysis was undertaken of all cases of Parkinson's syndrome seen at the
Massachusetts General Hospital between 1875 and 1961. There were 1383 recorded cases
which were suitable for analysis. Only 24 cases were located in the 43 years prior to 1918,
while 1359 cases were found in the ensuing 42 years. For all cases, the mean year of birth
was 1894.3 and the range (mean±2× sd) was 1866.7 to 1921.9. Between the group with
onset in 1920–1924 and the group with onset in 1955–1959, a period of 35 years, the mean …