Lisuride in parkinsonism

G Gopinathan, H Teravainen, JM Dambrosia… - Neurology, 1981 - AAN Enterprises
G Gopinathan, H Teravainen, JM Dambrosia, CD Ward, JN Sanes, WK Stuart, EV Evarts…
Neurology, 1981AAN Enterprises
we studied the actions of lisuride, a dopaminergic ergot derivative, in 20 parkinsonian
patients. When the dose was increased gradually, most patients tolerated up to 5 mg daily.
Clinical assessment and objective, computer-assisted evaluation revealed improvement in
akinesia, rigidity and tremor. Adverse reactions were similar to those seen with levodopa
and bromocriptine, but somnolence tended to occur more often with lisuride.
we studied the actions of lisuride, a dopaminergic ergot derivative, in 20 parkinsonian patients. When the dose was increased gradually, most patients tolerated up to 5 mg daily. Clinical assessment and objective, computer-assisted evaluation revealed improvement in akinesia, rigidity and tremor. Adverse reactions were similar to those seen with levodopa and bromocriptine, but somnolence tended to occur more often with lisuride.
American Academy of Neurology