[HTML][HTML] AdipoQ is a novel adipose-specific gene dysregulated in obesity (∗)
E Hu, P Liang, BM Spiegelman - Journal of biological chemistry, 1996 - ASBMB
Adipose differentiation is accompanied by changes in cellular morphology, a dramatic
accumulation of intracellular lipid and activation of a specific program of gene expression.
Using an mRNA differential display technique, we have isolated a novel adipose cDNA,
termed adipoQ. The adipoQ cDNA encodes a polypeptide of 247 amino acids with a
secretory signal sequence at the amino terminus, a collagenous region (Gly-XY repeats),
and a globular domain. The globular domain of adipoQ shares significant homology with …
accumulation of intracellular lipid and activation of a specific program of gene expression.
Using an mRNA differential display technique, we have isolated a novel adipose cDNA,
termed adipoQ. The adipoQ cDNA encodes a polypeptide of 247 amino acids with a
secretory signal sequence at the amino terminus, a collagenous region (Gly-XY repeats),
and a globular domain. The globular domain of adipoQ shares significant homology with …