[PDF][PDF] Activating AMP-activated protein kinase without AMP

MJ Birnbaum - Molecular cell, 2005 - cell.com
Molecular cell, 2005cell.com
Previews Page 1 Molecular Cell, Vol. 19, 289–296, August 5, 2005, Copyright ©2005 by
Elsevier Inc. DOI 10.1016/j.molcel.2005.07.012 Previews terized by hamartomatous
intestinal polyps (Spicer and Activating AMP-Activated Protein Ashworth, 2004). The
importance of AMPK to the conKinase without AMP trol of growth and survival is
incontestable, though its precise role in carcinogenesis remains uncertain, because LKB1 is
capable of regulating a number of other Though once believed to be regulated exclusively …
Though once believed to be regulated exclusively by the cellular energy state, AMPK has now been shown to be activated by a calcium-dependent signaling pathway.
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