A possible physiological role for glyceroneogenesis in rat adipose tissue
L Reshef, RW Hanson, FJ Ballard - Journal of Biological Chemistry, 1970 - ASBMB
Pyruvate decreased the rate of free fatty acid release from rat epididymal adipose tissue
incubated in vitro by increasing free fatty acid esterification. The magnitude of the pyruvate
effect, tested in tissues from fasted, adrenalectomized, or diabetic rats, closely correlated
both with the rate of glyceride-glycerol labeling from radioactive pyruvate and with the
activity of P-enolpyruvate carboxykinase. The addition of 25 mm pyruvate to adipose tissue
from 24-hour fasted rats produced a 2-fold increase in free fatty acid esterification. At a lower …
incubated in vitro by increasing free fatty acid esterification. The magnitude of the pyruvate
effect, tested in tissues from fasted, adrenalectomized, or diabetic rats, closely correlated
both with the rate of glyceride-glycerol labeling from radioactive pyruvate and with the
activity of P-enolpyruvate carboxykinase. The addition of 25 mm pyruvate to adipose tissue
from 24-hour fasted rats produced a 2-fold increase in free fatty acid esterification. At a lower …