Tumor infiltrating lymphocytes and macrophages have a potential dual role in lung cancer by supporting both host-defense and tumor progression

A Kataki, P Scheid, M Piet, B Marie, N Martinet… - Journal of Laboratory …, 2002 - Elsevier
A prerequisite to the developement of an efficient cell and/or gene therapy for lung cancer is
a precise characterization of the inflammatory cell populations spontaneously present in the
tumor stroma associated with this cancer. This study was designed to define the cytotoxic
potential and the relationship with stroma development of tumor infiltrating lymphocytes (TIL)
and tumor associated macrophages (TAM). Tumor samples from 48 patients undergoing
surgery for non-small cell lung cancer (NSCLC) were analyzed, by immunohistochemistry …