Centrally administered NPY stimulated gastric acid and pepsin secretion by a vagally mediated mechanism
M Matsuda, M Aono, M Moriga, M Okuma - Regulatory peptides, 1991 - Elsevier
We investigated the possible roles of centrally administered neuropeptide Y (NPY) on
gastric secretion, serum gastrin levels and gastric mucosal blood flow in anesthetized rats.
Centrally administered NPY dose-dependently stimulated gastric acid and pepsin secretion.
The stimulatory effect of intracerebroventricular administration of NPY was more potent than
that of intracisternal administration. Centrally administered NPY also increased gastric
secretion in the central noradrenaline depleted rats. In contrast, intravenously administered …
gastric secretion, serum gastrin levels and gastric mucosal blood flow in anesthetized rats.
Centrally administered NPY dose-dependently stimulated gastric acid and pepsin secretion.
The stimulatory effect of intracerebroventricular administration of NPY was more potent than
that of intracisternal administration. Centrally administered NPY also increased gastric
secretion in the central noradrenaline depleted rats. In contrast, intravenously administered …