Prospective study of maternal intake of vitamin D during pregnancy and risk of wheezing illnesses in children at age 2 years

CA Camargo, SL Rifas-Shiman, AA Litonjua… - Journal of Allergy and …, 2006 - jacionline.org
METHODS: Participants were 1,306 mother-child pairs in Project Viva, a prospective “pre-
birth” cohort study in Massachusetts. We assessed maternal intake of vitamin D from a
validated food frequency questionnaire in the first and second trimesters, and averaged
intake for analyses. We defined “any wheeze” as mother-reported wheeze during years 1 or
2 of life, and “recurrent wheeze” as wheeze in both years. Doctor diagnosis of “asthma” was
a composite of doctor-diagnosed asthma, wheezing, or reactive airway disease. RESULTS …