[HTML][HTML] Hypovitaminosis D is associated with insulin resistance and β cell dysfunction
Background Although the role of vitamin D in type 2 diabetes is well recognized, its relation
to glucose metabolism is not well studied. Objective We investigated the relation of 25-
hydroxyvitamin D [25 (OH) D] concentrations to insulin sensitivity and β cell function. Design
We enrolled 126 healthy, glucose-tolerant subjects living in California. Insulin sensitivity
index (ISI) and first-and second-phase insulin responses (1stIR and 2ndIR) were assessed
by using a hyperglycemic clamp. Results Univariate regression analyses showed that 25 …
to glucose metabolism is not well studied. Objective We investigated the relation of 25-
hydroxyvitamin D [25 (OH) D] concentrations to insulin sensitivity and β cell function. Design
We enrolled 126 healthy, glucose-tolerant subjects living in California. Insulin sensitivity
index (ISI) and first-and second-phase insulin responses (1stIR and 2ndIR) were assessed
by using a hyperglycemic clamp. Results Univariate regression analyses showed that 25 …