Inflammation and cancer: the long reach of Ras
M Karin - Nature Medicine, 2005 - nature.com
Nature Medicine, 2005•nature.com
For decades cancer biologists have thought of oncogenes in terms of their ability to prompt
tumor growth and survival, acting within the cancer cell. That viewpoint is now changing to
take into account data showing that oncogenes influence inflammation. Insights now emerge
from work on Ras and the proinflammatory mediator interleukin-8, produced by tumor-
infiltrating immune cells.
tumor growth and survival, acting within the cancer cell. That viewpoint is now changing to
take into account data showing that oncogenes influence inflammation. Insights now emerge
from work on Ras and the proinflammatory mediator interleukin-8, produced by tumor-
infiltrating immune cells.
For decades cancer biologists have thought of oncogenes in terms of their ability to prompt tumor growth and survival, acting within the cancer cell. That viewpoint is now changing to take into account data showing that oncogenes influence inflammation. Insights now emerge from work on Ras and the proinflammatory mediator interleukin-8, produced by tumor-infiltrating immune cells.
nature.com