Signal transduction using nitric oxide and cyclic guanosine monophosphate

F Murad - JAMA, 1996 - jamanetwork.com
Understanding of the formation and biological actions of nitric oxide (NO) has grown
extensively during the past 2 decades. Through our discoveries of the biological effects of
NO and nitrovasodilators on cyclic guanosine monophosphate (GMP) and our discoveries of
the biochemical mechanisms of NO and regulation of NO synthase in numerous cell types
and tissues, the complexity of the signal transduction cascade and the extensive function-
regulating interactions of the NO molecule have been increasingly demonstrated. Although …

The 1996 Albert Lasker Medical Research Awards. Signal transduction using nitric oxide and cyclic guanosine monophosphate.

F Murad - Jama, 1996 - europepmc.org
Understanding of the formation and biological actions of nitric oxide (NO) has grown
extensively during the past 2 decades. Through our discoveries of the biological effects of
NO and nitrovasodilators on cyclic guanosine monophosphate (GMP) and our discoveries of
the biochemical mechanisms of NO and regulation of NO synthase in numerous cell types
and tissues, the complexity of the signal transduction cascade and the extensive function-
regulating interactions of the NO molecule have been increasingly demonstrated. Although …