[HTML][HTML] Dietary L-arginine supplementation reduces fat mass in Zucker diabetic fatty rats
WJ Fu, TE Haynes, R Kohli, J Hu, W Shi… - The Journal of …, 2005 - Elsevier
This study was conducted to test the hypothesis that dietary supplementation of arginine, the
physiologic precursor of nitric oxide (NO), reduces fat mass in the Zucker diabetic fatty (ZDF)
rat, a genetically obese animal model of type-II diabetes mellitus. Male ZDF rats, 9 wk old,
were pair-fed Purina 5008 diet and received drinking water containing arginine-HCl (1.51%)
or alanine (2.55%, isonitrogenous control) for 10 wk. Serum concentrations of arginine and
NO x (oxidation products of NO) were 261 and 70% higher, respectively, in arginine …
physiologic precursor of nitric oxide (NO), reduces fat mass in the Zucker diabetic fatty (ZDF)
rat, a genetically obese animal model of type-II diabetes mellitus. Male ZDF rats, 9 wk old,
were pair-fed Purina 5008 diet and received drinking water containing arginine-HCl (1.51%)
or alanine (2.55%, isonitrogenous control) for 10 wk. Serum concentrations of arginine and
NO x (oxidation products of NO) were 261 and 70% higher, respectively, in arginine …