[HTML][HTML] Identification of LBM180, a lamellar body limiting membrane protein of alveolar type II cells, as the ABC transporter protein ABCA3
S Mulugeta, JM Gray, KL Notarfrancesco… - Journal of Biological …, 2002 - ASBMB
Lamellar bodies are the specialized secretory organelles of alveolar type II (ATII) epithelial
cells through which the cell packages pulmonary surfactant and regulates its secretion.
Surfactant within lamellar bodies is densely packed as circular arrays of lipid membranes
and appears to be the product of several trafficking and biosynthetic processes. To elucidate
these processes, we reported previously on the generation of a monoclonal antibody (3C9)
that recognizes a unique protein of the lamellar body membrane of 180 kDa, which we …
cells through which the cell packages pulmonary surfactant and regulates its secretion.
Surfactant within lamellar bodies is densely packed as circular arrays of lipid membranes
and appears to be the product of several trafficking and biosynthetic processes. To elucidate
these processes, we reported previously on the generation of a monoclonal antibody (3C9)
that recognizes a unique protein of the lamellar body membrane of 180 kDa, which we …