Z39Ig is co-expressed with activated macrophage genes
MG Walker - Biochimica et Biophysica Acta (BBA)-Gene Structure …, 2002 - Elsevier
Z39Ig is a recently-identified gene with immunoglobulin-like domains whose function is
unknown. We examined expression of Z39Ig in 1432 human cDNA libraries, and found it
primarily in synovium of patients with rheumatoid arthritis, in placenta, and in lung. We
analyzed its co-expression pattern using the Guilt-by-Association (GBA) algorithm, and
found that it is most similar in expression to early genes in the classical complement system
(C1qA, C1qB, C1qC, C1r, and C1 inhibitor), MHC class II genes (HLA-DR alpha, HLA-DR …
unknown. We examined expression of Z39Ig in 1432 human cDNA libraries, and found it
primarily in synovium of patients with rheumatoid arthritis, in placenta, and in lung. We
analyzed its co-expression pattern using the Guilt-by-Association (GBA) algorithm, and
found that it is most similar in expression to early genes in the classical complement system
(C1qA, C1qB, C1qC, C1r, and C1 inhibitor), MHC class II genes (HLA-DR alpha, HLA-DR …