Evaluation of myosin-reactive antibodies from a panel of myasthenia gravis patients

S Mohan, RJ Barohn, CE Jackson, KA Krolick - Clinical immunology and …, 1994 - Elsevier
In the study described below, 97 myasthenia gravis (MG) patients have been evaluated for
antibody reactivity against muscle myosin. With few exceptions, we could clearly observe a
positive correlation between the presence of circulating serum anti-myosin antibodies and
disease severity. Unlike some studies of anti-striational antibodies in MG patients, no
association with thymoma was apparent. Moreover, no relationships were revealed between
the severity of disease symptoms demonstrated and absolute anti-myosin antibody titers or …