Adenoviruses (Ads) are endemic in the human population and the well-studied group C Ads
typically cause an acute infection in the respiratory epithelium. A growing body of evidence
suggests that these viruses also establish a persistent infection. The Ad genome encodes
several proteins that counteract the host anti-viral mechanisms, which function to limit viral
infections. This review describes the adenovirus immuno-regulatory proteins and how they
function to block apoptosis of infected cells. In addition to facilitating the successful …