The complement system in bullous pemphigoid: II. Immunofluorescent evidence for both classical and alternate-pathway activation
RE Jordon, AL Schroeter, RA Good, NK Day - Clinical Immunology and …, 1975 - Elsevier
Skin lesions of 15 bullous pemphigoid patients were examined for the presence of Clq, C3,
C3 proactivator (C3PA), and properdin in addition to immunoglobulins (IgG, IgA, and IgM)
and fibrin using immunofluorescent (IF) techniques. Properdin and C3 were present along
the skin basement-membrane zone in all of the lesions studied in addition to
immunoglobulins. Deposition of C3PA was found in only 5 of 15 skin speciments with
considerably less staining intensity than that observed for C3 and properdin. Deposition of …
C3 proactivator (C3PA), and properdin in addition to immunoglobulins (IgG, IgA, and IgM)
and fibrin using immunofluorescent (IF) techniques. Properdin and C3 were present along
the skin basement-membrane zone in all of the lesions studied in addition to
immunoglobulins. Deposition of C3PA was found in only 5 of 15 skin speciments with
considerably less staining intensity than that observed for C3 and properdin. Deposition of …