Healing of diabetic foot ulcers and pressure ulcers with human skin equivalent: a new paradigm in wound healing

H Brem, J Balledux, T Bloom, MD Kerstein… - Archives of …, 2000 - jamanetwork.com
Hypothesis In patients with diabetic foot and pressure ulcers, early intervention with
biological therapy will either halt progression or result in rapid healing of these chronic
wounds. Design In a prospective nonrandomized case series, 23 consecutive patients were
treated with human skin equivalent (HSE) after excisional debridement of their wounds.
Setting A single university teaching hospital and tertiary care center. Patients and Methods
Twenty-three consecutive patients with a total of 41 wounds (1.0-7.5 cm in diameter) were …