Tumor eradication by adoptive transfer of cytototic T lymphocytes
CJM Melief - Advances in cancer research, 1992 - Elsevier
Publisher Summary This chapter discusses the eradication of tumor by adoptive transfer of
cytotoxic T lymphocytes. Complete and permanent eradication of tumors by
histocompatability complex (MHC) class I restricted CD8+ tumor-specific cytotoxic T
lymphocytes (CTLs) can be achieved in a variety of experimental murine models. In human
metastatic melanoma, CD8+ tumor-specific CTLs are probably therapeutically the most
active components among lymphokine-activated killer or tumor-infiltrating lymphocytes cells …
cytotoxic T lymphocytes. Complete and permanent eradication of tumors by
histocompatability complex (MHC) class I restricted CD8+ tumor-specific cytotoxic T
lymphocytes (CTLs) can be achieved in a variety of experimental murine models. In human
metastatic melanoma, CD8+ tumor-specific CTLs are probably therapeutically the most
active components among lymphokine-activated killer or tumor-infiltrating lymphocytes cells …