Indoleamine 2, 3-dioxygenase (IDO) is involved in promoting the development of anterior chamber-associated immune deviation
X Chen, L Liu, P Yang, C Wu, H Jin, L Xing, B Li… - Immunology letters, 2006 - Elsevier
Indoleamine 2, 3-dioxygenase (IDO), a rate-limiting enzyme in the tryptophan catabolism,
has been shown to play an important role in various forms of immune tolerance. Since
anterior chamber associated immune deviation (ACAID) is a systemic immune tolerance
elicited by introducing exogenous antigens into the anterior chamber of the eye, we
investigated the expression and function of IDO in the development of this ocular tolerance.
ACAID was induced in BALB/c mice by an intracameral injection of 50μg ovalbumin (OVA) …
has been shown to play an important role in various forms of immune tolerance. Since
anterior chamber associated immune deviation (ACAID) is a systemic immune tolerance
elicited by introducing exogenous antigens into the anterior chamber of the eye, we
investigated the expression and function of IDO in the development of this ocular tolerance.
ACAID was induced in BALB/c mice by an intracameral injection of 50μg ovalbumin (OVA) …